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A Mutation in the STN1 Gene Triggers an Alternative Lengthening of Telomere-Like Runaway Recombinational Telomere Elongation and Rapid Deletion in Yeast

Some human cancer cells achieve immortalization by using a recombinational mechanism termed ALT (alternative lengthening of telomeres). A characteristic feature of ALT cells is the presence of extremely long and heterogeneous telomeres. The molecular mechanism triggering and maintaining this pathway...

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Bibliografski detalji
Glavni autori: Iyer, Shilpa, Chadha, Ashley D., McEachern, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234331/
https://ncbi.nlm.nih.gov/pubmed/16135798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8064-8073.2005
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