Cell Cycle-Regulated Inactivation of Endothelial NO Synthase through NOSIP-Dependent Targeting to the Cytoskeleton

Nitric oxide (NO) plays a key role in vascular function, cell proliferation, and apoptosis. Proper subcellular localization of endothelial NO synthase (eNOS) is crucial for its activity; however, the role of eNOS trafficking for NO biosynthesis remains to be defined. Overexpression of NOS-interactin...

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Detalhes bibliográficos
Main Authors: Schleicher, Michael, Brundin, Fredrik, Gross, Steffen, Müller-Esterl, Werner, Oess, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234313/
https://ncbi.nlm.nih.gov/pubmed/16135813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8251-8258.2005
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