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Coding and Noncoding Genomic Regions of Entamoeba histolytica Have Significantly Different Rates of Sequence Polymorphisms: Implications for Epidemiological Studies

To evaluate genetic variability among Entamoeba histolytica strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection...

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Bibliografiske detaljer
Main Authors: Bhattacharya, Dhruva, Haque, Rashidul, Singh, Upinder
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234137/
https://ncbi.nlm.nih.gov/pubmed/16145147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.9.4815-4819.2005
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