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Aortic aneurysm in Marfan's syndrome: changes in the ultrastructure and composition of collagen.

Aneurysmal aortic tissue and the mitral valve of a patient with Marfan's syndrome were examined. Biochemical analysis of the tissue showed a qualitative and quantitative defect in alpha 2 chain production of Type I collagen. On polyacrylamide gel electrophoresis of the aortic extract, two separ...

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Autors principals: Scheck, M, Siegel, R C, Parker, J, Chang, Y H, Fu, J C
Format: Artigo
Idioma:Inglês
Publicat: 1979
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1233030/
https://ncbi.nlm.nih.gov/pubmed/541247
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