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The use of 5-(125I)iodo-2'-deoxyuridine for monitoring DNA synthesis in organ culture.

5-[125I]iodo-2'-deoxyuridine (125IUdR) has been shown to be effective in monitoring DNA synthesis in murine tumour and human benign prostatic hyperplasia explants maintained in organ culture for 2 days, thus making possible the rapid screening of antitumour drugs. Uptake was linear for at least...

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Main Authors: Riches, A C, Gore, D, Docherty, J, Littlewood, V
格式: Artigo
語言:Inglês
出版: 1976
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231803/
https://ncbi.nlm.nih.gov/pubmed/58855
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