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Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages

The expression of uncoupling protein 2 (UCP2) was reduced in macrophages after stimulation with lipopolysaccharide (LPS). The physiological consequence and the regulatory mechanisms of the UCP2 down-regulation by LPS were investigated in a macrophage cell line, RAW264 cells. UCP2 overexpression in R...

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Autores principales: Kizaki, Takako, Suzuki, Kenji, Hitomi, Yoshiaki, Taniguchi, Naoyuki, Saitoh, Daizoh, Watanabe, Kenji, Onoé, Kazunori, Day, Noorbibi K., Good, Robert A., Ohno, Hideki
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC123151/
https://ncbi.nlm.nih.gov/pubmed/12089332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142206299
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