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PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis

The human protein kinase X gene (PRKX) is a member of an ancient family of cAMP-dependent serine/threonine kinases here shown to be phylogenetically distinct from the classical PKA, PKB/Akt, PKC, SGK, and PKG gene families. Renal expression of the PRKX gene is developmentally regulated and restricte...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Li, Xiaohong, Li, Hsi-Ping, Amsler, Kurt, Hyink, Deborah, Wilson, Patricia D., Burrow, Christopher R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123128/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12082174/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132051799
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