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Humoral and Cell-Mediated Adaptive Immune Responses Are Required for Protection against Burkholderia pseudomallei Challenge and Bacterial Clearance Postinfection

Burkholderia pseudomallei, the causative agent of melioidosis, is a gram-negative bacillus endemic to areas of southeast Asia and northern Australia. Presently, there is no licensed vaccine for B. pseudomallei and the organism is refractive to antibiotic therapy. The bacterium is known to survive an...

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Détails bibliographiques
Auteurs principaux: Healey, Gareth D., Elvin, Stephen J., Morton, Margaret, Williamson, E. Diane
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231116/
https://ncbi.nlm.nih.gov/pubmed/16113315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5945-5951.2005
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