Pathogenicity and Immunogenicity of a Vaccine Strain of Listeria monocytogenes That Relies on a Suicide Plasmid To Supply an Essential Gene Product

Listeria monocytogenes is a bacterial pathogen that elicits a strong cellular immune response and thus has potential use as a vaccine vector. An attenuated strain, L. monocytogenes dal dat, produced by deletion of two genes (dal and dat) used for d-alanine synthesis, induces cytotoxic T lymphocytes...

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Bibliographic Details
Main Authors: Zhao, Xinyan, Li, Zhongxia, Gu, Baiyan, Frankel, Fred R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231070/
https://ncbi.nlm.nih.gov/pubmed/16113297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5789-5798.2005
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