Potent stimulation of transcription-coupled DNA supercoiling by sequence-specific DNA-binding proteins
Transcription by RNA polymerase can stimulate localized DNA supercoiling in Escherichia coli. In vivo, there is extensive experimental support for a “twin-domain” model in which positive DNA supercoils are generated ahead of a translocating RNA polymerase complex and negative supercoils are formed b...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12093906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.142002099 |
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