Optimization of Codon Usage Enhances the Immunogenicity of a DNA Vaccine Encoding Mycobacterial Antigen Ag85B

In spite of its many other benefits, DNA vaccine is limited in its application by its insufficient immunogenicity. One promising approach for enhancing its immunogenicity is to maximize its expression in the immunized host. In the current study, we investigated whether codon optimization of the myco...

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Bibliografiske detaljer
Main Authors: Ko, Hyun-Jeong, Ko, Sung-Youl, Kim, Yeon-Jeong, Lee, Eun-Gae, Cho, Sang-Nae, Kang, Chang-Yuil
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231050/
https://ncbi.nlm.nih.gov/pubmed/16113284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5666-5674.2005
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