Massive Destruction of Malaria-Parasitized Red Blood Cells despite Spleen Closure

It is currently accepted that malaria-parasitized red blood cells (pRBC) are eliminated, like senescent erythrocytes, phagocytically by macrophages in the red pulp of the spleen. Here, however, we show that self-healing Plasmodium chabaudi malaria activates spleen closure in C57BL/6 mice. Confocal l...

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Detalhes bibliográficos
Main Authors: Krücken, Jürgen, Mehnert, Liv I., Dkhil, Mohamed A., El-Khadragy, Manal, Benten, W. Peter M., Mossmann, Horst, Wunderlich, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230986/
https://ncbi.nlm.nih.gov/pubmed/16177310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6390-6398.2005
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