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Inhibition of Cell Surface Export of Group A Streptococcal Anchorless Surface Dehydrogenase Affects Bacterial Adherence and Antiphagocytic Properties

Surface dehydrogenase (SDH) is an anchorless, multifunctional protein displayed on the surfaces of group A Streptococcus (GAS) organisms. SDH is encoded by a single gene, sdh (gap or plr) that is essential for bacterial survival. Hence, the resulting nonfeasibility of creating a knockout mutant is a...

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Autores principales: Boël, Grégory, Jin, Hong, Pancholi, Vijay
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230963/
https://ncbi.nlm.nih.gov/pubmed/16177295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6237-6248.2005
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