Alteration in Host Cell Tropism Limits the Efficacy of Immunization with a Surface Protein of Malaria Merozoites

Immunization with Plasmodium yoelii merozoite surface protein-8 (PyMSP-8) has been shown to protect mice against lethal P. yoelii 17XL malaria. Here we demonstrate that PyMSP-8-specific antibodies preferentially suppress P. yoelii 17XL growth in mature erythrocytes compared to growth in reticulocyte...

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Bibliografiske detaljer
Main Authors: Shi, Qifang, Cernetich, Amy, Daly, Thomas M., Galvan, Gina, Vaidya, Akhil B., Bergman, Lawrence W., Burns, James M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230925/
https://ncbi.nlm.nih.gov/pubmed/16177307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6363-6371.2005
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