Major Histocompatibility Complex Class II Inhibits Fas Antigen-Mediated Gastric Mucosal Cell Apoptosis through Actin-Dependent Inhibition of Receptor Aggregation

Escape from normal apoptotic controls is thought to be essential for the development of cancer. During Helicobacter pylori infection, the leading cause of gastric cancer, activation of the Fas antigen (Fas Ag) apoptotic pathway is responsible for early atrophy and tissue loss. As disease progresses,...

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Autori principali: Stoicov, Calin, Cai, Xun, Li, Hanchen, Klucevsek, Kristine, Carlson, Jane, Saffari, Reza, Houghton, JeanMarie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1230908/
https://ncbi.nlm.nih.gov/pubmed/16177302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.10.6311-6321.2005
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