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Basic FGF mediates an immediate response of articular cartilage to mechanical injury

The extracellularly regulated kinase (ERK), one of the three types of mitogen-activated kinases, was rapidly activated after cutting porcine articular cartilage either when maintained as explants or in situ. Cutting released a soluble ERK-activating factor from the cartilage, which was purified and...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Vincent, Tonia, Hermansson, Monika, Bolton, Mark, Wait, Robin, Saklatvala, Jeremy
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.122033199
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