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Constitutive activation of Stat5a by retrovirus integration in early pre-B lymphomas of SL/Kh strain mice

We found that the second intron of Stat5a was one of the common integration sites of the endogenous ecotropic murine leukemia virus, i.e., SL/Kh virus integration-1 (Svi1), in early pre-B lymphomas in SL/Kh mice. The high expression of STAT5A induced by Svi1 integration and activation accelerated th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsuruyama, Tatsuaki, Nakamura, Takuro, Jin, Guang, Ozeki, Munetaka, Yamada, Yoshihiro, Hiai, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123054/
https://ncbi.nlm.nih.gov/pubmed/12048235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112202899
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