Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination

Myelin/oligodendrocyte glycoprotein (MOG) is a target antigen for myelin-destructive Abs in autoimmune central nervous system demyelinating disorders. Little is known about the molecular and structural basis of these pathogenic Ab responses. Here, we have characterized anti-MOG Ab specificities in t...

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Autors principals: von Büdingen, Hans-Christian, Hauser, Stephen L., Fuhrmann, Antje, Nabavi, Cameron B., Lee, Joy I., Genain, Claude P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC123046/
https://ncbi.nlm.nih.gov/pubmed/12060766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122092499
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