Allogeneic β-islet cells correct diabetes and resist immune rejection

Allogeneic MHC-incompatible organ or cell grafts are usually promptly rejected by immunocompetent hosts. Here we tested allogeneic β-islet cell graft acceptance by immune or naïve C57BL/6 mice rendered diabetic with streptozotocin (STZ). Fully MHC-mismatched insulin-producing growth-regulated β-isle...

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Detalhes bibliográficos
Main Authors: Pericin, Marcus, Althage, Alana, Freigang, Stefan, Hengartner, Hans, Rolland, Eric, Dupraz, Philippe, Thorens, Bernard, Aebischer, Patrick, Zinkernagel, Rolf M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123045/
https://ncbi.nlm.nih.gov/pubmed/12060765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122241299
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