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cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions

We have investigated the role of cAMP in NO- and prostanoid-independent relaxations that are widely attributed to an endothelium-derived hyperpolarizing factor (EDHF). Under control conditions EDHF-type relaxations evoked by acetylcholine (ACh) in rabbit iliac arteries were transient, but in the pre...

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Главные авторы: Griffith, Tudor M., Chaytor, Andrew T., Taylor, Hannah J., Giddings, Beverley D., Edwards, David H.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC122959/
https://ncbi.nlm.nih.gov/pubmed/11972050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092089799
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