Neutrophils are indispensable for hematopoietic stem cell mobilization induced by interleukin-8 in mice

The CXC chemokine interleukin-8 (IL-8/CXCL8) induces rapid mobilization of hematopoietic progenitor cells (HPCs). Previously we showed that mobilization could be prevented completely in mice by pretreatment with neutralizing antibodies against the β2-integrin LFA-1 (CD11a). In addition, murine HPCs...

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Detalhes bibliográficos
Main Authors: Pruijt, Johannes F. M., Verzaal, Perry, van Os, Ronald, de Kruijf, Evert-Jan F. M., van Schie, Marianke L. J., Mantovani, Alberto, Vecchi, Annunciata, Lindley, Ivan J. D., Willemze, Roel, Starckx, Sofie, Opdenakker, Ghislain, Fibbe, Willem E.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122931/
https://ncbi.nlm.nih.gov/pubmed/11983913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092112999
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