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Regulation of transcription by H1 phosphorylation in Tetrahymena is position independent and requires clustered sites

In Tetrahymena cells, constitutive phosphorylation of histone H1 phenocopies the loss of H1 from chromatin. Regulation of transcription by H1 phosphorylation is achieved by altering the overall charges of a small domain. Here, we further explore the electrostatic properties of this domain and the me...

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Autori principali: Dou, Yali, Gorovsky, Martin A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122916/
https://ncbi.nlm.nih.gov/pubmed/11972045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092029599
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