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Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography
Activation of G protein-coupled receptors (GPCRs) is triggered and regulated by structural rearrangement of the transmembrane heptahelical bundle containing a number of highly conserved residues. In rhodopsin, a prototypical GPCR, the helical bundle accommodates an intrinsic inverse-agonist 11-cis-r...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The National Academy of Sciences
2002
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122888/ https://ncbi.nlm.nih.gov/pubmed/11972040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082666399 |
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