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Modulation of tRNA(Ala) identity by inorganic pyrophosphatase

A highly sensitive assay of tRNA aminoacylation was developed that directly measures the fraction of aminoacylated tRNA by following amino acid attachment to the 3′-(32)P-labeled tRNA. When applied to Escherichia coli alanyl-tRNA synthetase, the assay allowed accurate measurement of aminoacylation o...

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Hlavní autoři: Wolfson, Alexey D., Uhlenbeck, Olke C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122885/
https://ncbi.nlm.nih.gov/pubmed/11983895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092152799
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