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The crystal structure of exonuclease RecJ bound to Mn(2+) ion suggests how its characteristic motifs are involved in exonuclease activity

RecJ, a 5′ to 3′ exonuclease specific for single-stranded DNA, functions in DNA repair and recombination systems. We determined the crystal structure of RecJ bound to Mn(2+) ion essential for its activity. RecJ has a novel fold in which two domains are interconnected by a long helix, forming a centr...

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Bibliographische Detailangaben
Hauptverfasser: Yamagata, Atsushi, Kakuta, Yoshimitsu, Masui, Ryoji, Fukuyama, Keiichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122875/
https://ncbi.nlm.nih.gov/pubmed/11972066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092547099
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