The crystal structure of exonuclease RecJ bound to Mn(2+) ion suggests how its characteristic motifs are involved in exonuclease activity
RecJ, a 5′ to 3′ exonuclease specific for single-stranded DNA, functions in DNA repair and recombination systems. We determined the crystal structure of RecJ bound to Mn(2+) ion essential for its activity. RecJ has a novel fold in which two domains are interconnected by a long helix, forming a centr...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122875/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11972066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092547099 |
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