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The identification of functional modules from the genomic association of genes

By combining the pairwise interactions between proteins, as predicted by the conserved co-occurrence of their genes in operons, we obtain protein interaction networks. Here we study the properties of such networks to identify functional modules: sets of proteins that together are involved in a biolo...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Snel, Berend, Bork, Peer, Huynen, Martijn A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122872/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11983890/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.092632599
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