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Precision and functional specificity in mRNA decay

Posttranscriptional processing of mRNA is an integral component of the gene expression program. By using DNA microarrays, we precisely measured the decay of each yeast mRNA, after thermal inactivation of a temperature-sensitive RNA polymerase II. The half-lives varied widely, ranging from ∼3 min to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yulei, Liu, Chih Long, Storey, John D., Tibshirani, Robert J., Herschlag, Daniel, Brown, Patrick O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122867/
https://ncbi.nlm.nih.gov/pubmed/11972065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092538799
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