IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase

Toll/IL-1 receptor family members are central components of host defense mechanisms in a variety of species. One well conserved element in their signal transduction is Ser/Thr kinases, which couple early signaling events in a receptor complex at the plasma membrane to larger signalosomes in the cyto...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Li, Shyun, Strelow, Astrid, Fontana, Elizabeth J., Wesche, Holger
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11960013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082100399
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