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Unspecific hydrophobic stabilization of folding transition states

Here we present a method for determining the inference of non-native conformations in the folding of a small domain, α-spectrin Src homology 3 domain. This method relies on the preservation of all native interactions after Tyr/Phe exchanges in solvent-exposed, contact-free positions. Minor changes i...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Viguera, Ana Rosa, Vega, Cristina, Serrano, Luis
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122772/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072387799
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