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A peptide template as an allosteric supramolecular catalyst for the cleavage of phosphate esters

The heptapeptide H-Iva-Api-Iva-ATANP-Iva-Api-Iva-NHCH(3) (P1a), where Iva is (S)-isovaline, Api is 4-amino-4-carboxypiperidine, and ATANP is (S)-2-amino-3-[1-(1,4,7-triazacyclononane)]propanoic acid, has been synthesized. Its conformation in aqueous solution is essentially that of a 3(10)-helix. By...

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Detalhes bibliográficos
Main Authors: Scarso, Alessandro, Scheffer, Ute, Göbel, Michael, Broxterman, Quirinus B., Kaptein, Bernard, Formaggio, Fernando, Toniolo, Claudio, Scrimin, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122736/
https://ncbi.nlm.nih.gov/pubmed/11943857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072642699
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