Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection

In the penis, nitric oxide (NO) can be formed by both neuronal NO synthase and endothelial NOS (eNOS). eNOS is activated by viscous drag/shear stress in blood vessels to produce NO continuously, a process mediated by the phosphatidylinositol 3-kinase (PI3kinase)/Akt pathway. Here we show that PI3-ki...

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Detalles Bibliográficos
Main Authors: Hurt, K. Joseph, Musicki, Biljana, Palese, Michael A., Crone, Julie K., Becker, Robyn E., Moriarity, John L., Snyder, Solomon H., Burnett, Arthur L.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC122648/
https://ncbi.nlm.nih.gov/pubmed/11904450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052712499
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