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Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism

Thyroid hormone (T3) controls critical aspects of cerebellar development, such as migration of postmitotic granule cells and terminal differentiation of Purkinje cells. T3 acts through nuclear receptors (TR) of two types, TRα1 and TRβ, that either repress or activate gene expression. We have analyze...

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Detaylı Bibliyografya
Asıl Yazarlar: Morte, Beatriz, Manzano, Jimena, Scanlan, Thomas, Vennström, Björn, Bernal, Juan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC122635/
https://ncbi.nlm.nih.gov/pubmed/11891331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062413299
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