Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line

Immunity to Plasmodium falciparum in African children has been correlated with antibodies to the P. falciparum erythrocyte membrane protein 1 (PfEMP1) variant gene family expressed on the surface of infected red cells. We immunized Aotus monkeys with a subregion of the Malayan Camp variant antigen (...

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Autores principales: Baruch, Dror I., Gamain, Benoit, Barnwell, John W., Sullivan, JoAnn S., Stowers, Anthony, Galland, G. Gale, Miller, Louis H., Collins, William E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2002
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC122614/
https://ncbi.nlm.nih.gov/pubmed/11904437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022018399
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