Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes

Previous studies showed that antagonists of bombesin (BN)/gastrin-releasing peptide (GRP) inhibit the growth of various cancers by interfering with the growth-stimulatory effects of BN-like peptides and down-regulating epidermal growth factor receptors on tumors. Because the overexpression of the hu...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Bajo, Ana M., Schally, Andrew V., Krupa, Magdalena, Hebert, Francine, Groot, Kate, Szepeshazi, Karoly
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2002
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11891317/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052715299
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