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Study of mechanisms of electric field-induced DNA transfection. V. Effects of DNA topology on surface binding, cell uptake, expression, and integration into host chromosomes of DNA in the mammalian cell.

Neumann and coworkers (Neumann, E., M. Schaefer-Ridder, Y. Wang, and P. H. Hofschneider. 1982. EMBO J. 1:841-845) have shown that the efficiency of pulsed electric field (PEF)-induced DNA transfection of mouse L-cells by the thymidine kinase gene is several times higher for the linear DNA than for t...

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Bibliographic Details
Main Authors: Xie, T. D., Tsong, T. Y.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225895/
https://ncbi.nlm.nih.gov/pubmed/8274656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-3495(93)81208-6
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