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Histidine substitution identifies a surface position and confers Cs+ selectivity on a K+ pore.

The amino acid located at position 369 is a key determinant of the ion conduction pathway or pore of the voltage-gated K+ channels, Kv2.1 and a chimeric channel, CHM, constructed by replacing the pore region of Kv2.1 with that of Kv3.1. To determine the orientation of residue 369 with respect to the...

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Detalhes bibliográficos
Main Authors: De Biasi, M, Drewe, J A, Kirsch, G E, Brown, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225843/
https://ncbi.nlm.nih.gov/pubmed/8241404
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