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Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration
Elevated hyaluronan biosynthesis and matrix deposition correlates with cell proliferation and migration. We ectopically expressed three isoforms of hyaluronan synthase (HAS1, HAS2, or HAS3) in nontransformed rat 3Y1 cells and observed a de novo, massive formation of a hyaluronan matrix that resulted...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122571/ https://ncbi.nlm.nih.gov/pubmed/11891291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052026799 |
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