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Neutrophils lacking phosphoinositide 3-kinase γ show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

Confocal imaging and time-lapsed videomicroscopy were used to study the directionality, motility, rate of cell movement, and morphologies of phosphoinositide 3-kinase γ (PI3K)γ(−/−) neutrophils undergoing chemotaxis in Zigmond chambers containing N-formyl-Met-Leu-Phe gradients. Most of the PI3Kγ(−/−...

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Detaylı Bibliyografya
Asıl Yazarlar: Hannigan, Michael, Zhan, Lijun, Li, Zhong, Ai, Youxi, Wu, Dianqing, Huang, Chi-Kuang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC122570/
https://ncbi.nlm.nih.gov/pubmed/11904423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052010699
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