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Mutation of the myosin converter domain alters cross-bridge elasticity

Elastic distortion of a structural element of the actomyosin complex is fundamental to the ability of myosin to generate motile forces. An elastic element allows strain to develop within the actomyosin complex (cross-bridge) before movement. Relief of this strain then drives filament sliding, or mor...

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Hlavní autoři: Köhler, Jan, Winkler, Gerhard, Schulte, Imke, Scholz, Tim, McKenna, William, Brenner, Bernhard, Kraft, Theresia
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC122562/
https://ncbi.nlm.nih.gov/pubmed/11904418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062415899
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