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Effect of acid predissolution on fibril size and fibril flexibility of synthetic beta-amyloid peptide.

beta-amyloid peptide (A beta) is the major protein component of senile plaques and cerebrovascular amyloid deposits in Alzheimer's patients. Several researchers have demonstrated that A beta is neurotoxic in in vitro and in vivo systems. Peptide aggregation state and/or conformation might play...

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Bibliografische gegevens
Hoofdauteurs: Shen, C L, Fitzgerald, M C, Murphy, R M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1994
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225480/
https://ncbi.nlm.nih.gov/pubmed/7811938
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