Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 Å resolution: Mimicking the product/substrate of the phospho transfer reactions

The histidine containing phospho carrier protein (HPr) kinase/phosphatase is involved in carbon catabolite repression, mainly in Gram-positive bacteria. It is a bifunctional enzyme that phosphorylates Ser-46-HPr in an ATP-dependent reaction and dephosphorylates P-Ser-46-HPr. X-ray analysis of the fu...

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Detalhes bibliográficos
Main Authors: Márquez, José Antonio, Hasenbein, Sonja, Koch, Brigitte, Fieulaine, Sonia, Nessler, Sylvie, Russell, Robert B., Hengstenberg, Wolfgang, Scheffzek, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122545/
https://ncbi.nlm.nih.gov/pubmed/11904409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052461499
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