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Conformational transitions of duplex and triplex nucleic acid helices: thermodynamic analysis of effects of salt concentration on stability using preferential interaction coefficients.

For order-disorder transitions of double- and triple-stranded nucleic acid helices, the midpoint temperatures Tm depend strongly on a +/-, the mean ionic activity of uniunivalent salt. Experimental determinations of dTm/d ln a +/- and of the enthalpy change (delta H(o)) accompanying the transition i...

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Autors principals: Bond, J. P., Anderson, C. F., Record, M. T.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225425/
https://ncbi.nlm.nih.gov/pubmed/7948695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-3495(94)80542-9
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