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Covalent modification of proteins by cocaine
Cocaine covalently modifies proteins through a reaction in which the methyl ester of cocaine acylates the ɛ-amino group of lysine residues. This reaction is highly specific in vitro, because no other amino acid reacts with cocaine, and only cocaine's methyl ester reacts with the lysine side cha...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122537/ https://ncbi.nlm.nih.gov/pubmed/11891282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042700599 |
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