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Covalent modification of proteins by cocaine

Cocaine covalently modifies proteins through a reaction in which the methyl ester of cocaine acylates the ɛ-amino group of lysine residues. This reaction is highly specific in vitro, because no other amino acid reacts with cocaine, and only cocaine's methyl ester reacts with the lysine side cha...

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Bibliografske podrobnosti
Main Authors: Deng, Shi-Xian, Bharat, Narine, Fischman, Marian C., Landry, Donald W.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC122537/
https://ncbi.nlm.nih.gov/pubmed/11891282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042700599
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