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Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences
RNase P complexes have been proposed as a novel RNA-based gene interference strategy to inhibit gene expression in human malignancies and infectious diseases. This approach is based on the sequence-specific design of an external guide sequence (EGS) RNA molecule that can specifically hybridize to al...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122536/ https://ncbi.nlm.nih.gov/pubmed/11904403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052651199 |
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