Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells

Heptahelical receptors (HHRs) are generally thought to function as monomeric entities. Several HHRs such as somatostatin receptors (SSTRs), however, form homo- and heterooligomers when activated by ligand binding. By using dual fluorescent ligands simultaneously applied to live cells monotransfected...

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Autori principali: Patel, Ramesh C., Kumar, Ujendra, Lamb, Don C., Eid, John S., Rocheville, Magalie, Grant, Michael, Rani, Aruna, Hazlett, Theodore, Patel, Shutish C., Gratton, Enrico, Patel, Yogesh C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122512/
https://ncbi.nlm.nih.gov/pubmed/11880655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042705099
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