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Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm
Vascular occlusion is the major cause of morbidity and mortality in sickle cell disease but its mechanisms are poorly understood. We demonstrate by using intravital microscopy in mice expressing human sickle hemoglobin (SS) that SS red blood cells (RBCs) bind to adherent leukocytes in inflamed venul...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122470/ https://ncbi.nlm.nih.gov/pubmed/11880644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052522799 |
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