Primary role for adherent leukocytes in sickle cell vascular occlusion: A new paradigm

Vascular occlusion is the major cause of morbidity and mortality in sickle cell disease but its mechanisms are poorly understood. We demonstrate by using intravital microscopy in mice expressing human sickle hemoglobin (SS) that SS red blood cells (RBCs) bind to adherent leukocytes in inflamed venul...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Turhan, Aslihan, Weiss, Linnea A., Mohandas, Narla, Coller, Barry S., Frenette, Paul S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11880644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052522799
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