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Kar3 interaction with Cik1 alters motor structure and function

Kar3, a kinesin-14 motor of Saccharomyces cerevisiae required for mitosis and karyogamy, reportedly interacts with Cik1, a nonmotor protein, via its central, predicted coiled coil. Despite this, neither Kar3 nor Cik1 homodimers have been observed in vivo. Here we show that Kar3 is a dimer in vitro b...

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Detalhes bibliográficos
Main Authors: Chu, Hsiao Mei Annie, Yun, Mikyung, Anderson, David E, Sage, Harvey, Park, Hee-Won, Endow, Sharyn A
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224680/
https://ncbi.nlm.nih.gov/pubmed/16107877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600790
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