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Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen

Three genome-wide RNA interference screens were performed in Drosophila S2 cells to dissect the contribution of host processes to Listeria monocytogenes entry, vacuolar escape, and intracellular growth. Among the 116 genes identified, several host pathways previously unrecognized as playing a role i...

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Detalhes bibliográficos
Main Authors: Cheng, Luisa W., Viala, Julie P. M., Stuurman, Nico, Wiedemann, Ursula, Vale, Ronald D., Portnoy, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224656/
https://ncbi.nlm.nih.gov/pubmed/16157870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506461102
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