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Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments
Following transfer into lymphopenic hosts, naive CD8 T cells proliferate and acquire memory phenotype. Although the acquired phenotype is stable in recombination activating gene-1-deficient (RAG(−/−)) recipients, in sublethally irradiated mice naive CD8 T cells of donor origin gradually accumulate....
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122460/ https://ncbi.nlm.nih.gov/pubmed/11880642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052714099 |
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